Structural Optimization of Pyrazolo[1,5-A]pyrimidine Derivatives As Potent and Highly Selective DPP-4 Inhibitors
European Journal of Medicinal Chemistry（2020）
关键词
Type 2 diabetes mellitus (T2DM),DPP-4 inhibitor,Pyrazolo[1,5-a]pyrimidine derivatives,Fragment-based drug design,Scaffold hopping
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