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Subcellular Localization and Formation of Huntingtin Aggregates Correlates with Symptom Onset and Progression in A Huntington’S Disease Model

Christian Landles,Rebecca E. Milton,Nadira Ali,Rachel Flomen,Michael Flower,Franziska Schindler,Casandra Gomez-Paredes,Marie K. Bondulich,Georgina F. Osborne,Daniel Goodwin, Grace Salsbury,Caroline L. Benn,Kirupa Sathasivam,Edward J. Smith,Sarah J. Tabrizi,Erich E. Wanker,Gillian P. Bates

Brain communications（2020）

引用 26|浏览69
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关键词
Huntington's disease,polyglutamine,huntingtin aggregation and seeding,transcriptional dysregulation,somatic CAG instability
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