MYOPATHY WITH RAGGED-RED FIBERS FOLLOWING RENAL-TRANSPLANTATION - POSSIBLE ROLE OF CYCLOSPORINE-INDUCED HYPOMAGNESEMIA
ACTA NEUROPATHOLOGICA(1994)
摘要
A 65-year-old man developed a painless proximal myopathy 7 years after commencing cyclosporin therapy following a successful cadaveric renal transplant. Muscle histology showed ragged red fibres and biochemical studies suggested mitochondrial dysfunction. The possible pathogenesis of this mitochondrial myopathy, particularly its relationship to cyclosporin-induced hypomagnesaemia, is discussed.
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关键词
CYCLOSPORINE,HYPOMAGNESEMIA,MITOCHONDRIAL MYOPATHY,RENAL TRANSPLANTATION
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