Synthesis and SAR of a Series of Mglu7 NAMs Based on an Ethyl-8-methoxy-4-(4-phenylpiperazin-1-yl)quinoline Carboxylate Core.

Bioorganic & Medicinal Chemistry Letters(2020)

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关键词
mGlu(7),Metabotropic glutamate receptor,Negative Allosteric modulator (NAM),Structure-activity-relationship (SAR)
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