Prognostic factors for long-term survival after pancreaticoduodenectomy for periampullary adenocarcinoma. A retrospective cohort study

•Periampullary adenocarcinoma (PAAC) is highly aggressive tumor.•It has late diagnosis with poor prognosis.•Pancreaticoduodenectomy (PD) is still the only curative treatment option.•PD surgery is associated with high morbidity and mortality.•It is important to determine which patients who can receive benefit from surgery.