Association Between Physical Activity Intensity Levels and Arterial Stiffness in Healthy Children.

BACKGROUND:Physical activity (PA) has a substantial impact on arterial stiffness in adults; however, evidence regarding children is scarce. The aim of this study was to examine the association between objectively measured PA with different intensities and surrogate measures of arterial stiffness in healthy children.METHODS:Altogether, 80 children (41 girls and 39 boys, ranging from 8-11 y) participated in this prospective, cross-sectional study. Sedentary time and PA of light, moderate, and vigorous intensity levels were measured over a period of 7 days by accelerometry. Arterial stiffness parameters, including pulse wave velocity and central systolic blood pressure (cSBP), were noninvasively assessed by the oscillometric Mobil-O-Graph. Associations were tested using multiple linear regressions with adjustments for potential confounders (α ≤ .05).RESULTS:PA of moderate intensity was negatively associated with cSBP (β = -0.266, P = .017). PA of vigorous intensity was inversely related to pulse wave velocity (β = -0.225, P = .045) and cSBP (β = -0.286, P = .010), respectively.CONCLUSION:Higher time spent in PA of moderate and vigorous intensity is associated with reduced pulse wave velocity and lower cSBP values in children. It suggests that PA is a favorable determinant of arterial health.