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Design and Synthesis of a Highly Selective and in Vivo-Capable Inhibitor of the Second Bromodomain of the Bromodomain and Extra Terminal Domain Family of Proteins

Alex Preston, Stephen Atkinson,Paul Bamborough,Chun-wa Chung,Peter D. Craggs,Laurie Gordon,Paola Grandi,James R. J. Gray,Emma J. Jones,Matthew Lindon,Anne-Marie Michon,Darren J. Mitchell,Rab K. Prinjha,Francesco Rianjongdee,Inmaculada Rioja,Jonathan Seal,Simon Taylor,Ian Wall,Robert J. Watson,James Woolven,Emmanuel H. Demont

Journal of Medicinal Chemistry（2020）

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