Primary Hepatic Lymphoma: Three Case Reports And A Literature Review

Primary hepatic lymphoma (PHL) is a rare malignant tumor. In this article, three cases of PHL initially misdiagnosed as benign tumors or other malignancies are reported. Clinical manifestations, laboratory examinations, and imaging all presented nonspecific findings leading to the puzzling diagnoses. Definite diagnoses were made according to immunohistochemistry of specimens acquired either through liver biopsy or hepatolobectomy. Two cases of diffused large B-Cell lymphoma and one little T-Cell lymphoma were found. Therefore, PHL should be taken into consideration in differential diagnoses of occupied intrahepatic lesions. Our report focuses on the imaging features of PHL in order to improve the understanding of PHL, and how restricted diffusion and enhancement patterns on MRI should be helpful to differential diagnoses.