Polymorphisms in MEN 1 and DRD 2 genes are associated with the occurrence and characteristics 1 of pituitary adenomas 2

Polymorphisms in MEN1 and DRD2 genes are associated with the occurrence and characteristics 1 of pituitary adenomas 2 Raitis Peculis 1 , Inga Balcere 2,4 , Vita Rovite 1 , Kaspars Megnis 1 , Andra Valtere 3, Janis Stukens 2 , 3 Ligita Arnicane 3 , Liene Nikitina-Zake 1 , Aivars Lejnieks 3 , Valdis Pirags 1,2,4 , Janis Klovins 1 4 Author affiliation 5 1 Latvian Biomedical Research and Study Centre, Ratsupites iela 1, Riga, LV-1067, Latvia 6 2 Pauls Stradiņš Clinical University Hospital, Pilsonu iela 13, Riga, LV-1002, Latvia 7 3 Riga Eastern Clinical University Hospital, Hipokrata iela 2, Riga, LV-1038, Latvia 8 4 University of Latvia, Faculty of Medicine, Raina bulv. 19, Riga, LV 1586, Latvia 9 Corresponding author 10 Janis Klovins, Latvian Biomedical Research and Study Centre, Ratsupites iela 1, Riga, LV-1067, 11 Latvia, klovins@biomed.lu.lv 12 Short title 13 MEN1 and DRD2 impact pituitary adenomas 14