The Serum C 3 d levels in tropical pulmonary eosinophilia

interstitial lung disease that results from an exaggerated immune response to filarial parasites Wuchereria bancrofti and Brugia malayi1. TPE has been reported from filarial endemic regions from all over the world but is especially common in India and South East Asia1,2. The disease is characterized by wheezing, pulmonary infiltrates and marked peripheral blood eosinophilia. Patients with TPE demonstrate very high levels of IgE and filarial specific antibodies1-3. Studies on possible role of complement system in TPE has so far used only the classical methods like serum haemolytic component of the complement (CH50), serum C3 and C4 levels4,5. The Serum C3d levels in tropical pulmonary eosinophilia