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Low-dose oncolytic adenovirus therapy overcomes tumor-induced immune suppression and sensitizes intracranial gliomas to anti-PD-1 therapy.

Zineb Belcaid,Cor Berrevoets,John Choi,Edward van Beelen,Eftychia Stavrakaki, Tessa Pierson,Jenneke Kloezeman,Denis Routkevitch,Mariëlle van der Kaaij, Alicia van der Ploeg,Dimitrios Mathios,Stefan Sleijfer,Clemens Dirven,Michael Lim,Reno Debets,Martine L M Lamfers

Neuro-oncology advances（2020）

引用 26|浏览69
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摘要
This study demonstrates the potential of using low-dose Delta24-RGD therapy to sensitize glioma for combination with anti-PD-1 antibody therapy.
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关键词
Delta24-RGD,PD-1,glioma,immunotherapy,oncolytic virotherapy
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