Canine immunoglobulin F(ab′)2 fragments protect cats against feline parvovirus virus infection

Zhihua Pei, Mingjie Sun, Xuezhu Zhang, Yan Yan, Fanru Meng,Ruo Mo,Haijun Wang,Junzheng Wang,Kai Wang,Guixue Hu

International Immunopharmacology（2020）

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摘要

•Canine immunoglobulin F(ab′)2 fragments showed efficient neutralizing activity in vitro against FPV.•Canine immunoglobulin F(ab′)2 fragments had therapeutic and prophylactic effects in FPV infected cats.•F(ab′)2 fragment may be used as a prophylactic and therapeutic agent for diseases caused by FPV.

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关键词

Feline parvovirus virus,Canine,F(ab′)2 fragment,Cat

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