New acridine derivatives as promising agents against methicillin-resistant staphylococci – From tests to in silico analysis
Computational Biology and Chemistry(2020)
摘要
•Antibacterial activity of several new derivatives of tacrine.•Tested methicillin-resistant staphylococci.•Quantitative structure-activity relationship analysis.•Relationships between biological activity and the structural parameters.•Select descriptors as independent variables for multiple linear regression models.
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关键词
Acridine derivatives,Methicillin-resistant staphylococci,Antibacterial activity,MIC,MBC
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