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Genetic reduction of cilium length by targeting intraflagellar transport 88 protein impedes kidney and liver cyst formation in mouse models of autosomal polycystic kidney disease

Lina Shao,Wassim El-Jouni, Fanwu Kong,Janani Ramesh, Radhe Shantha Kumar,Xiaogang Shen, Jingjing Ren, Shruti Devendra,Arianna Dorschel,Maoqing Wu, Ivan Barrera,Azadeh Tabari,Kang Hu, Nadeem Haque,Ilyas Yambayev, Shiqi Li, Amresh Kumar,Tapas Ranjan Behera, Gregory McDonough, Masahito Furuichi, Michael Xifaras,Tzongshi Lu, Rami Mohammad Alhayaza, Koji Miyabayashi, Qiuling Fan,Amrendra K. Ajay,Jing Zhou

Kidney international(2020)

引用 33|浏览30
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关键词
beta-catenin,cystogenesis,Pkd1 knockout,Pkd2.lft88 double knockout,primary cilia
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