Factors Associated with Ovarian Preservation in Children and Adolescents with Primary Tumors of Ovary

To determine management of pediatric ovarian masses and identify the factors associated with ovarian preservation. From January, 2002 to January, 2019 the case records of 72 patients (median age 14 y), who underwent surgery for ovarian tumors were retrospectively reviewed. Tumors were most common in the age group 14’17 yrs (58.3%) and most (91.7%) were benign. The most common presenting symptom was abdominal pain (80.5%) followed by vomiting, elevated body temperature, nausea and palpable abdominal mass. 25 (34.7%) patients had an ovarian torsion. Six out of 72 (8.3%) patients had malignant tumors. Of the patients with malignant tumors, 75% had abnormal alpha-fetoprotein and 50% had abnormal β-human chorionic gonadotropin levels (P<0.001). Ovarian-preserving surgery was successfully performed in 74.3% of the benign lesions and two patients (25%) with malignant tumors (P=0.004). Factors associated with ovarian-preserving surgery are benign tumor, normal tumor markers levels, and smaller size of tumor.