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Digoxin Treatment Reverses Angiogenic Switch During HeartMate 3 Support and is Associated with Decrease Risk for Gastrointestinal Bleeding.

S. Vukelic, N. Sibinga,P. Vlismas,C. Alvarez,D. Sims,O. Saeed,J. Shin,S. Forest,S. Patel, D. Goldstein,U. P. Jorde

˜The œjournal of heart and lung transplantation/˜The œJournal of heart and lung transplantation（2020）

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Abstract
Digoxin, an inhibitor of HIF1-α signaling cascade, may contribute to a lower risk of GIB in HM3 patients by restoring angiogenic equilibrium.
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