Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase-1 (IDO1).
Catherine White,Meredeth A McGowan,Hua Zhou,Nunzio Sciammetta,Xavier Fradera,Jongwon Lim,Elizabeth M Joshi,Christine Andrews,Elliott B Nickbarg, Phillip Cowley, Sarah Trewick,Martin Augustin, Konstanze von Köenig,Charles A Lesburg,Karin Otte,Ian Knemeyer,Hyun Woo,Wensheng Yu,Mangeng Cheng,Peter Spacciapoli,Prasanthi Geda,Xuelei Song,Nadya Smotrov,Patrick Curran,Mee Ra Heo,Pravien Abeywickrema,J Richard Miller,David Jonathan Bennett,Yongxin Han ACS medicinal chemistry letters（2020）
Key words
IDO1,heme displacer,oxetane,AlogP(98)
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