Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries

Doris Mia Taylor,Justin Anglin,Suhyeorn Park,Melek N. Ucisik,John C. Faver,Nicholas Simmons,Zhuang Jin,Murugesan Palaniappan,Pranavanand Nyshadham,Feng Li,James Campbell,Liya Hu,Banumathi Sankaran,B. V. Venkataram Prasad,Hongbing Huang,Martin M. Matzuk,Timothy Palzkill

ACS INFECTIOUS DISEASES（2020）

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关键词

beta-lactam antibiotic,beta-lactamase,carbapenemase,OXA-48,drug discovery,DNA-encoded library,DECL,DEC-Tec

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