Recent advances in novel drug delivery systems and approaches for management of breast cancer: A comprehensive review

Breast Cancer (BC) is a carcinoma of breast tissues, the major recurrent cancer in women and also the foremost cause of death with approximate 5 million annual deaths worldwide. The most developed regions of the world show the highest incidence rate of BC when compared to less developed regions. However, the mortality rate was found to be higher in developing countries. In women with less than 40 years of age, approximately 7% diagnosed as suffering from BC and in women with less than 35 years of age, it was less than 4%. Presently less curative options are available for such patients. Emerging novel delivery systems may result in a promising approach for its early recognition and efficient treatment. Currently, cancer research focuses on improving BC treatment using various novel delivery systems of chemotherapeutic agents such as nanoformulations, liposomes, hydrogels, exosomes, dendrimers, microspheres, microbubbles, phytosomes, micelles, etc. The present review encloses existing assorted novel drug delivery systems and approaches intended for diagnosis and treatment of BC.