Mouse Heterochromatin Adopts Digital Compaction States Without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation

Fabian Erdel,Anne Rademacher,Rifka Vlijm,Jana Tuennermann,Lukas Frank,Robin Weinmann, Elisabeth Schweigert,Klaus Yserentant,Johan Hummert,Caroline Bauer,Sabrina Schumacher, Ahmad Al Alwash,Christophe Normand,Dirk-Peter Herten,Johann Engelhardt,Karsten Rippe

Molecular Cell（2020）

引用 162|浏览22

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Heterochromatin protein 1,nuclear organization,chromatin compartmentalization,chromatin accessibility,liquid- liquid phase separation,polymer collapse,intracellular viscosity,optodroplets,polarization-dependent fluorescence correlation spectroscopy,epigenetic editing

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