Structure-Guided Design of Substituted Biphenyl Butanoic Acid Derivatives As Neprilysin Inhibitors.
Toshio Kawanami,Rajeshri G. Karki, Emma Cody,Qian Liu,Guiqing Liang,Gary M. Ksander,Dean F. Rigel,Nikolaus Schiering,Yongjin Gong,Gary M. Coppola,Yuki Iwaki,Robert Sun,Alan Neubert, Li Fan, Sara Ingles,Allan D'Arcy,Frederic Villard,Paul Ramage,Arco Y. Jeng,Jennifer Leung-Chu,Jing Liu,Michael Beil,Fumin Fu, Wei Chen,Frederic Cumin,Christian Wiesmann,Muneto Mogi ACS Medicinal Chemistry Letters（2020）
关键词
Neprilysin,crystal structure,structure-based design,structure-activity relationship
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