Structure-based Design and Optimization of Pyrimidine- and 1,2,4-Triazolo[4,3-a]pyrimidine-based Matrix Metalloproteinase-10/13 Inhibitors Via Dimroth Rearrangement Towards Targeted Polypharmacology.
Bioorganic Chemistry(2020)
关键词
MMP-10/13,Polypharmacology,Pyrimidine,Triazolopyrimidine,Dimroth rearrangement,Anticancer
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