Nerolidol inhibits the LOX-1 / IL-1β signaling to protect against the Aspergillus fumigatus keratitis inflammation damage to the cornea.
International Immunopharmacology(2020)
摘要
•Nerolidol protected the corneas from infection by inhibiting the growth of Aspergillus fumigatus.•Nerolidol played a protective role to corneal transparency in mouse A. fumigatus keratitis.•Nerolidol impaired LOX-1/IL-1β signaling in mice corneas and HCECs infected by A. fumigatus.
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关键词
Keratitis,Aspergillus fumigatus,Nerolidol,LOX-1,IL-1β
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