The Dntpase Activity of SAMHD1 is Important for Its Suppression of Innate Immune Responses in Differentiated Monocytic Cells
The Journal of biological chemistry（2020）
Key words
SAM domain and HD domain-containing protein 1 (SAMHD1),innate immunity,NF-kB transcription factor,interferon,cell differentiation,monocyte,inflammation,NF-kappa B (NF-KB),dNTPase activity,innate immune responses,nuclear localization,SAMHD1,NF-?B activation,type I interferon (IFN-I),monocytic cells,viral restriction factor
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