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Oxygen Saturation Recovery after Six-Minute Walk Test and Body Composition in COPD and HF Subjects

Epidemiology(2019)

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摘要
Background: Chronic Pulmonary Obstructive Disease (COPD) and Heart Failure (HF) has body composition alterations and decreased in functional capacity, with important repercussions on clinical status and prognosis. However, there is not enough evidence about the relation between the oxygen saturation (SPo2) recovery and body composition COPD and HF subjects. Objectives: To evaluate the relation between SPo2 recovery after six-minute walk and body composition in COPD and HF subjects. Materials and Methods: Cross sectional study, COPD and HF diagnosis, older than 40 years were included, those with asthma diagnosis were excluded. Oxygen saturation recovery capacity was determinate value > 80 of SPo2 difference between recovery period and end of the 6-minute walk test, grip strength was determined by dynamometer, body composition by Bioelectric impedance vectorial analysis. Results: 120 COPD and HF subjects were included, mean age was 68.5±12.2. Patients with low SPo2 recovery capacity had more total body water (50±8.8 vs 46.3±8.2, p=0.07), extracellular water (23.3±5.6 vs 21.2±2.7, p= 0.07), as well less phase angle (4.7 ± 0.8 vs 5.2 ± 1.1, p=0.02), basal SPo2 (86.4 ± 6.8 vs 91.37 ± 4.5, p= 0.0005) and body weight (73.9 ± 20.9 vs 81.8 ± 22.3, p=0.07) than SPo2 recovery capacity subjects. Conclusions: Low oxygen saturation recovery capacity had greater body composition alterations, this had an important impact on prognosis in COPD and HF subjects.
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关键词
Chronic diseases,Acute respiratory failure,Hypoxia
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