High-Throughput Implementation of the NanoBRET Target Engagement Intracellular Kinase Assay to Reveal Differential Compound Engagement by SIK2/3 Isoforms
SLAS discovery(2020)
Key words
target engagement (TE),bioluminescence resonance energy transfer (BRET),NanoBRET,high-throughput screening (HTS),salt-inducible kinase (SIK),time-resolved fluorescence resonance energy transfer (TR-FRET)
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