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PTPN2 Phosphatase Deletion in T Cells Promotes Anti-Tumour Immunity and CAR T-cell Efficacy in Solid Tumours.

Florian Wiede,Kun-Hui Lu,Xin Du,Shuwei Liang,Katharina Hochheiser,Garron T. Dodd,Pei K. Goh,Conor Kearney,Deborah Meyran,Paul A. Beavis,Melissa A. Henderson,Simone L. Park,Jason Waithman, Sheng Zhang,Zhong-Yin Zhang,Jane Oliaro,Thomas Gebhardt,Phillip K. Darcy,Tony Tiganis

EMBO JOURNAL（2020）

引用 62|浏览74
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关键词
adoptive T-cell therapy,CAR T cells,protein tyrosine phosphatase N2,STAT-5 signalling,TCR signalling
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