Intensification of medical management in type 2 diabetes: A real-world look at primary care practice.

Journal of Diabetes and its Complications(2020)

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摘要
•A retrospective chart review of electronic medical record data; in primary care practice in Fairview Health System, Minnesota.•Assess second-line drugs selected and HbA1c and BMI outcomes at 6 and 12 months for patients with diabetes on metformin.•Sulfonylurea and basal insulin were the most common second-line anti-diabetic agents prescribed after metformin.•Patients treated with sulfonylurea, basal insulin or GLP-1 agonists added to metformin had significant reductions in HbA1c.•Patients prescribed a GLP-1 agonist had a higher mean baseline BMI and a significant BMI reduction from baseline.
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关键词
BMI,DPP-4,GLP-1,GRADE,HbA1c,SGLT-2,TZD,T2DM
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