PEAR1 suppresses the proliferation of pulmonary microvascular endothelial cells via PI3K/AKT pathway in ALI model.

Microvascular Research（2020）

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摘要

•The expression level of PEAR1 significantly increases in ALI model.•PEAR1 knockdown enhances the proliferation of human pulmonary microvascular endothelial cells (HPMECs).•PEAR1 mediates HPMECs proliferation via PI3K/AKT pathway.

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关键词

PEAR1,Proliferation,HPMEC,ALI

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