Role of Cardiovascular Biomarkers in the Risk Stratification, Monitoring, and Management of Patients with Cancer
Cardiology Clinics(2019)
摘要
Cardiovascular effects of cancer therapies are of concern. Prediction, diagnosis, and management of cardiotoxicity is a challenge. Cardiovascular biomarkers are being studied in relationship to cancer therapy, showing promise in detection and prevention of cardiotoxicity. We summarize the use of biomarkers in cardio-oncology and presents recommendations for their use. Troponins and natriuretic peptides are the most commonly used biomarkers. High-quality evidence supporting their use is lacking. Biomarkers can be incorporated into a detection strategy for cardiotoxicity. Large, well-powered studies are needed to delineate care strategies using biomarkers in the prediction and management of the cardiovascular effects of cancer therapy.
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关键词
Biomarkers,Troponin,Brain natriuretic peptide,Cardiotoxicity,Cancer,Chemotherapy,Anthracycline,Trastuzumab
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