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Evaluation of a Series of β-Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads.

Daniel Oehlrich,Aldo Peschiulli,Gary Tresadern,Michiel Van Gool,Juan Antonio Vega,Ana Isabel De Lucas,Sergio A Alonso de Diego,Hana Prokopcova,Nigel Austin,Sven Van Brandt,Michel Surkyn,Michel De Cleyn,Ann Vos,Frederik J R Rombouts,Gregor Macdonald,Dieder Moechars,Harrie J M Gijsen,Andrés A Trabanco

ACS medicinal chemistry letters（2019）

引用 17|浏览54
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关键词
BACE inhibitor,beta-secretase 1,Alzheimer's disease,cyclic sulfamidates,pK(a)
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