Protein kinase A-induced phosphorylation at the Thr154 affects stability of DJ-1

Parkinsonism & Related Disorders（2019）

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摘要

•PKAcα phosphorylates PARK7/DJ1 at the Thr154 residue.•Disruption of Thr154 phosphorylation is linked to a lower stability.

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关键词

DJ-1,Protein kinase A,Dimerization,Stability,Parkinson's disease

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