S144. Obesity is Associated With Anhedonia Only in the Younger Amish Women

We recently reported a significant gender-specific association between obesity and cardinal symptoms of depression; (i.e., anhedonia and dysphoria/hopelessness) in the Amish women, but not in men. Having in mind possible hormonal mediation of those differences, we further investigated these associations stratified by age-groups approximating the pre- versus post-menopausal divide.