Characterization of Excipient Effects on Reversible Self-Association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 1.
Journal of Pharmaceutical Sciences（2020）
关键词
monoclonal antibody,protein-protein interactions,reversible self-association,phase separation,excipient effects,hydrogen exchange-mass spectrometry,colloidal stability,local dynamics
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