C8-substituted Pyrido[3,4-D]pyrimidin-4(3h)-ones: Studies Towards the Identification of Potent, Cell Penetrant Jumonji C Domain Containing Histone Lysine Demethylase 4 Subfamily (KDM4) Inhibitors, Compound Profiling in Cell-Based Target Engagement Assays
Yann-Vaï Le Bihan,Rachel M Lanigan,Butrus Atrash,Mark G McLaughlin,Srikannathasan Velupillai,Andrew G Malcolm,Katherine S England,Gian Filippo Ruda,N Yi Mok,Anthony Tumber,Kathy Tomlin,Harry Saville,Erald Shehu,Craig McAndrew,LeAnne Carmichael,James M Bennett,Fiona Jeganathan,Paul Eve,Adam Donovan,Angela Hayes,Francesca Wood,Florence I Raynaud,Oleg Fedorov,Paul E Brennan,Rosemary Burke,Rob L M van Montfort,Olivia W Rossanese,Julian Blagg,Vassilios Bavetsias European journal of medicinal chemistry(2019)
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