Detection of Circulating Tumor Cells Based on Improved SERS-active Magnetic Nanoparticles

Ting Xue,Siqi Wang,Guoyu Ou,Yong Li,Huimin Ruan,Zihou Li,Yuanyuan Ma,Ruifen Zou,Jiaoyan Qiu,Zheyu Shen,Aiguo Wu

Analytical methods（2019）

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摘要

A SERS-active magnetic nanoparticle was developed for capture, enrichment and detection of cancer cells from blood samples. The isolated CTCs can also be released for further cell expansion, phenotype identification and molecular analysis.

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