Indium-, Magnesium-, and Zinc-Mediated Debenzylation of Protected 1H-Tetrazoles: A Comparative Study

Cherif Behloul,Meriem Benlahrech,Francisco Foubelo,Carmen Nájera,Miguel Yus

SYNTHESIS-STUTTGART（2018）

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摘要

5-Substituted 1-benzyltetrazoles are easily debenzylated to give the corresponding deprotected tetrazoles using dissolved metals under protic conditions: Mg/MeOH, In/MeOH, or Zn/MeCO2H are the procedures of choice for this transformation.

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debenzylation,magnesium,indium,zinc,tetrazoles

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Indium-, Magnesium-, and Zinc-Mediated Debenzylation of Protected­ 1H-Tetrazoles: A Comparative Study

Indium-, Magnesium-, and Zinc-Mediated Debenzylation of Protected 1H-Tetrazoles: A Comparative Study