Analysis of plasmid-mediated quinolone and oxyimino-cephalosporin resistance mechanisms in Uruguayan Salmonella enterica isolates from 2011–2013

•Quinolone and oxyimino-cephalosporin resistance reached 18.4% and 1.6%, respectively, in Uruguayan Salmonella enterica isolates.•Multiresistance was detected in 68% of the analysed isolates.•Uruguayan S. enterica isolates harboured CTX-M-8, CTX-M-14, CMY-2 or SHV-2 ESBLs.•PMQR genes (qnrB19 and qnrB2) were detected in 12.4% of ciprofloxacin-non-susceptible isolates.•Several S. Typhimurium clones circulate in Uruguay, whereas S. Enteritidis is monoclonal.