Intestinal dysbacteriosis mediates the reference memory deficit induced by anaesthesia/surgery in aged mice.

X L Jiang,X Y Gu,X X Zhou,X M Chen,X Zhang, Y T Yang,Y Qin, L Shen,W F Yu,D S Su

Brain, Behavior, and Immunity（2019）

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摘要

•Anaesthesia/surgery altered the gut microbiome in aged mice.•Dysbacteriosis induced by anaesthesia/surgery impaired reference memory in aged mice.•Probiotics alleviated reference memory impairment induced by anaesthesia/surgery.

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关键词

Gut microbiome,Intestinal dysbacteriosis,Postoperative cognitive dysfunction

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