Structure—activity Relationship in the Series of 1,3,4-6Н-thiadiazines Correcting Metabolic Disorders in Experimental Diabetes Mellitus

V. V. Emelianov,A. V. Ivanov,E. A. Savateeva,L. P. Sidorova,T. A. Tseitler,I. F. Gette,T. S. Bulavintseva,I. G. Danilova,N. E. Maksimova,N. N. Mochul´skaya,O. N. Chupakhin,V. A. Chereshnev

Russian chemical bulletin（2017）

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摘要

The corrective action of 1,3,4-6Н-thiadiazines in experimental diabetes mellitus was studied. The structure—activity relationship model for this series of compounds was proposed using the multiple linear regression method.

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关键词

1,3,4-6H-thiadiazines,alloxan-induced diabetes mellitus,hyperglycemia,structure-activity relationship

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