Outer membrane vesicles engineered to express membrane-bound antigen program dendritic cells for cross-presentation to CD8+ T cells

Sjoerd T.T. Schetters,Wouter S.P. Jong,Sophie K. Horrevorts,Laura J.W. Kruijssen,Steef Engels,Dorian Stolk,Maria H. Daleke-Schermerhorn,Juan Garcia-Vallejo,Diane Houben,Wendy W.J. Unger,Joke M.M. den Haan,Joen Luirink,Yvette van Kooyk

Acta Biomaterialia（2019）

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关键词

Outer membrane vesicles,Dendritic cells,Maturation,Antigen presentation,Cross-presentation,Cytotoxic T cells,Adaptive immunity,Vaccine,Antigen vehicle,MyD88,Innate signaling

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