USP7: combining tools towards selectivity.
CHEMICAL COMMUNICATIONS(2019)
摘要
Active-site directed probes based on the ubiquitin scaffold have been successfully applied as tools to determine the levels of active deubiquitinating enzymes (DUBs). Here, we show the development of a Ub-based reagent selective for the DUB USP7. This concept can be applied for the generation of other new selective reagents.
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关键词
selectivity,tools,usp7
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