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Human Ipsc-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate That Photoreceptors and Müller Glia Are Targets of AAV5.

Peter M. Quinn,Thilo M. Buck,Aat A. Mulder,Charlotte Ohonin,C. Henrique Alves,Rogier M. Vos,Monika Bialecka,Tessa van Herwaarden,Elon H. C. van Dijk,Mays Talib,Christian Freund,Harald M. M. Mikkers, Rob C. Hoeben,Marie-Jose Goumans,Camiel J. F. Boon,Abraham J. Koster,Susana M. Chuva de Sousa Lopes,Carolina R. Jost,Jan Wijnholds

Stem Cell Reports（2019）

Cited 65|Views86
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Key words
CRB1,CRB2,organoids,cell polarity,Müller glial cells,photoreceptors,adeno-associated virus,human induced pluripotent stem cells,retina,CRB1 patients
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