Quantitative Proteomics Reveals Changes in Transporter Protein Abundance in Liver, Kidney and Brain of Mice by Pregnancy.

Michael Z Liao,Chunying Gao,Deepak Kumar Bhatt,Bhagwat Prasad,Qingcheng Mao

Drug metabolism letters（2018）

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摘要

Protein abundance of drug transporters can be significantly changed particularly in the liver by pregnancy. These results will be helpful to understand pregnancy-induced changes in drug/xenobiotic disposition in the mouse model.

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关键词

Pregnancy,brain,kidney,liver,mass spectrometry,pregnant mice,quantitative proteomics,transporter.

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