Evolution of the Synthesis of AMPK Activators for the Treatment of Diabetic Nephropathy: from Three Preclinical Candidates to the Investigational New Drug PF-06409577 Aaron C. Smith , Daniel W. Kung , Andre Shavnya , Thomas A. Brandt , Philip D. Dent , Nathan E. Genung , Shawn Cabral , Jane Panteleev , Michael Herr , Ka Ning Yip , Gary E. Aspnes , Edward L. Conn , Matthew S. Dowling , David J. Edmonds , Ian D. Edmonds , Dilinie P. Fernando , Paul M. Herrinton , Nandell F. Keene , Sophie Y. Lavergne , Qifang Li , Jana Polivkova , Colin R. Rose , Benjamin A. Thuma , Michael G. Vetelino , Guoqiang Wang , John D. Weaver , Daniel W. Widlicka , Kristin E. Price Wiglesworth , Jun Xiao , Todd Zahn , Yingxin Zhang Organic process research & development（2018）
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