Abstract 13033: Titin Mutations in IPS Cells Define Sarcomere Insufficiency as a Cause of Dilated Cardiomyopathy (Best of Basic Science Abstract)

J. Travis Hinson,Anant Chopra,Sandra Swist,Craig C. Benson,Calvin Sheng, Navid A Nafissi,William J. Polacheck,Norbert Hubner,Wolfgang A. Linke, Stuart A. Cook,Christopher S. Chen,Jonathan G. Seidman,Christine E. Seidman

Circulation（2015）

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摘要

Introduction: Dilated cardiomyopathy (DCM) is one of the most common cardiovascular disorders with a prevalence of 1:250 patients. Patients with DCM develop left ventricular dilation, systolic dysf...

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关键词

Titin,Cardiomyopathy,Stem Cell Biology,Genetics,Genomics

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