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Design, Synthesis and Structure-Activity Relationships of Novel Macrolones: Hybrids of 2-Fluoro 9-Oxime Ketolides and Carbamoyl Quinolones with Highly Improved Activity Against Resistant Pathogens

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY(2019)

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关键词
Erythromycin,Ciprofloxacin,Multi-drug resistance,Ribosome,Erythromycin ribosomal methylation,Macrolide efflux
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