Amelioration of Autoimmune Arthritis in Mice Treated With the DNA Methyltransferase Inhibitor 5'-Azacytidine.

Dániel M Tóth, Timea Ocskó,Attila Balog,Adrienn Markovics,Katalin Mikecz,László Kovács,Meenakshi Jolly,Aleksandra A Bukiej,Andrew D Ruthberg,András Vida,Joel A Block,Tibor T Glant,Tibor A Rauch

Arthritis & rheumatology (Hoboken, N.J.)（2019）

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摘要

DNA hypermethylation plays a leading role in the pathogenesis of autoimmune arthritis and its targeted inhibition has therapeutic potential in arthritis management.

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关键词

autoimmune arthritis,dna methyltransferase inhibitor

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