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Incidental Meningiomas: Validation of a Novel Scoring System to Stratify Risk for Progression

Journal of clinical oncology(2018)

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摘要
e14024Background: Meningiomas are common incidental findings on brain imaging. Although most are indolent, some exhibit rapid growth posing a clinical dilemma for monitoring growth in the absence of robust predictive data. Recently proposed Asan Intracranial Meningioma Scoring System (AIMSS) [1] attempts to stratify growth risk based on imaging features. It scores tumor diameter (i) ( < 25mm, 25mm-39mm, or ≥40mm as 0, 3 or 6 respectively), absence vs. presence of hypointense T2 signal (ii), peritumoral edema (iii) and calcification (iv) (0 vs. 2, 0 vs. 1, and 0 vs. 2, respectively). Scores 0-2 suggest low risk vs. scores 3-11 represent intermediate-to-high risk for rapid tumor growth. The current study’s aim is to assess the relationship between AIMSS and meningioma growth rate (GR), and validate it in a North-American population using the RANO progression free survival (PFS) criteria[2]. Methods: We retrospectively enrolled 92 patients with incidental meningiomas (mean±SD age 62±14y; 73F) with at least 2...
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