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    • Pyrrole: An insight into recent pharmacological advances with structure activity relationship

    Shujauddin Ahmad,Ozair Alam,Mohd. Javed Naim,Mohammad Shaquiquzzaman,M. Mumtaz Alam,Muzaffar Iqbal

    European Journal of Medicinal Chemistry（2018）SCI 1区

    Medicinal Chemistry and Molecular Modelling Lab | Dept. of Pharmaceutical Chemistry

    Cited 167|Views17
    Abstract
    Pyrrole is a heterocyclic ring template with multiple pharmacophores that provides a way for the generation of library of enormous lead molecules. Owing to its vast pharmacological profile, pyrrole and its analogues have drawn much attention of the researchers/chemists round the globe to be explored exhaustively for the benefit of mankind. This review focusses on recent advancements; pertaining to pyrrole scaffold, discussing various aspects of structure activity relationship and its bioactivities.
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    Pyrrole,Anticancer,Antimicrobial,Structure activity relationship
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    【要点】：本文综述了近期关于吡咯结构活性关系及其药理学进展，重点讨论了吡咯支架的多样生物活性。
    

    【方法】：文章采用了文献回顾的方式，系统分析了吡咯及其类似物的结构-活性关系。
    

    【实验】：本文未涉及具体的实验过程，也没有提及使用的数据集名称和结果。
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